All entries by this author

Engineering Applications in Genomics

Nov 17th, 2014 | By

Lecture 1



Texas A&M HSC Institute of Biosciences and Technology Visits

Aug 1st, 2014 | By

The faculty from the Texas A&M Institute of Biosciences and Technology came to tour our building and visit with the faculty of the CBGSE. Dr. Datta presented an overview of the CBGSE and our faculty.    



Ultramodern genetic sequencing machine puts research in high gear at Texas A&M

Jul 17th, 2014 | By

The latest in genomic technologies along with new, spacious facilities has put genetic sequencing into high gear at Texas A&M University in College Station, officials said.



ARC: Soil Remediaon Workshop (South Africa)

Jun 23rd, 2014 | By

Dr. Johnson speaks at 1st annual ARC:Soil Remediaton Workshop (South Africa)



Structural genomics

May 4th, 2014 | By

Researchers: Yu Peng Evolution-based methods are currently among the most successful ones in predicting protein structures. The central idea is that evolution information, derived based on protein sequences alone, can be used to guide protein folding. We are interested in developing new methods to predict protein structures using rapidly accumulating HTS data.



Metagenomics

May 4th, 2014 | By

Researchers: Yu Peng Metagenomics is the direct sequencing and analysis of microbial communities in environmental or host-constrained samples, which offers a viable way to study more than 99% of all microbes that are unculturable. But analyses of complex mixtures of organisms remain challenging. We are interested in developing new analysis methods to understand the composition and

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Genomics of complex diseases

May 4th, 2014 | By

Researchers: Yu Peng Complex diseases, such as Autism Spectrum Disorders, are caused by a combination of genetic and environmental factors. The non-Mendelian inheritance pattern of these diseases has defeated attempts to predict the occurrence of these diseases based on genomic information. We address this challenge by developing novel computational methods using systems biology approaches such as

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Regulation of gene expression

May 4th, 2014 | By

Researchers: Yu Peng Eukaryote gene expression is tightly controlled to give arise to different cell types and tissues. To understand transcription regulation, we develop new computational methods by integrating ChIP-seq, DNA methylation, nucleosome positioning, CLIP-seq and RNA-seq data. We closely work with experimental biologists to validate our predictions.



Statistical HTS data analysis

May 4th, 2014 | By

Researchers: Yu Peng High-throughput sequencing technologies are widely used in biology experiments. These experiments typically have few biological replicates because of, for example, budget and time constraints. Our lab develops powerful and statistical rigorous methods to maximally extract information from these experiments that would otherwise not be possible.



Applications in Modeling Infectious Disease Processes

May 4th, 2014 | By

Researchers: Ulisses Braga-Neto This work is part of a long-standing collaboration with Dr. Ernesto Marques’ research groups at the at the Johns Hopkins Medical School (Dr. Marques’ previous affiliation), the University of Pittsburgh’s Center for Vaccine Research, and the Oswaldo Cruz Foundation (FIOCRUZ), in Recife, Brazil. The focus of this collaboration is the application of Genomic

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