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The Max Planck Research Group "Biological Clocks" (http://www.evolbio.mpg.de/biologicalclocks) combines evolutionary genomics and molecular biology with behavioral experiments and ecological fieldwork, aiming to uncover the yet unknown molecular basis of circalunar clocks. At the same time, we study the process of evolutionary adaptation. Our model organism, the intertidal midge Clunio marinus (Diptera), has timed its life cycle to the rhythm of the tides using circalunar and circadian clocks. As the tides differ along the coastline, the clocks of Clunio populations are genetically adapted to the local pattern of the tides. We have shown that these evolutionary adaptations can be exploited for comparative genomic and molecular studies in order to identify new clock molecules (Nature, in press).
The Max Planck Institute for Plant Breeding Research (MPIPZ) in Cologne, Germany, invites applications for a PhD position in the field of bioinformatics, genome assembly and plant genomics. The position is available in the Genome Plasticity and Computational Genetics headed by Dr Korbinian Schneeberger. Background / Objectives The focus of our group involves the development of methods for the analysis of high-throughput sequencing data (including Illumina, PacBio and Oxford Nanopore data), as well as the application of these methods in plant genetics/genomics. We develop new and creative methods to analyze genomes including reconstruction of the genome sequence (genome assembly) and analysis of differences to other genomes (genome comparison) covering all topics of sequence bioinformatics. We apply these methods to understand the dynamics of genomes and how they change over time - in short term over a few generations as well as over long evolutionary scales - as well as how these genomic differences encode for differences in the phenotypes. The initial project of the selected candidate will include the analysis and comparison of plants from an inter-species cross between two related plants. We will analyze how the chromosomes of such hybrid plants (each cell carries the genomes of two species) rearrange and mutate over the initial generation after crossing. It is known that the combination of chromosome sets of different species leads to drastic rearrangements. However, it is not clear how and what speed these mutations are introduced happens. The candidate will be involved in design of the sequence experiment, computational data analyses (including development of methods and approaches) of the genomes and interpretation of the results as well as in defining follow-up experiments. Payment / Position The position is available immediately. Selected candidates will be invited for interview. Salary and working hours are in accordance with the funding guidelines of the Max Planck Society for junior scientists. Working hours are fulltime; salary is 50 % of E13 TVöD-Bund. The Max-Planck society is committed to increasing the number of individuals with disabilities in its workforce and therefore encourages applications from such qualified individuals. Furthermore, the Max Planck Society seeks to increase the number of women in those areas where they are underrepresented and therefore explicitly encourages women to apply.
The Regulatory Genomics Laboratory at the Max Planck Institute for Molecular Biomedicine in Muenster, Germany is offering a ZENCODE-ITN PhD Position in Epigenetics and Computational Biology (position code 15-2016) The Laboratory, headed by Juan M Vaquerizas, seeks to appoint a highly motivated scientist to work on computational analyses of genome organisation and evolution as part of the ZENCODE-ITN (www.birmingham.ac.uk/zencode-itn). The scientific focus of the ZENCODE ITN consortium is to understand genome regulation through combined experimental and computational approaches in a model vertebrate. In particular, the successful candidate will analyse genome-wide gene expression and chromatin binding datasets at early stages of zebrafish embryonic development to investigate how developmental gene expression programmes are deployed. The project will focus on the analysis of mobile elements and their impact in the regulation of early embryonic development, and will be performed in close collaboration with Ferenc Mueller and Boris Lenhard’s laboratories. Terms of employment Applicants of any nationality must, at the time of recruitment (1 October 2016) be in the first 4 years (full-time equivalent) of their research careers after their first degree, which would entitle them to embark on a doctorate. Due to mobility requirement, only individuals who have not been resident in the host country (Germany) for more than 12 months in the last 3 years may apply. The position will be funded according to the regulations of the “Marie Sklodowska-Curie Actions”, a EU-framework program for research and innovation. How to apply Applications should be sent as a single PDF file by email via the
1 Postdoctoral and 1 PhD Position on Network Structures in Multitrophic Plant-Microbe and Microbe-Microbe Interactions The Max Planck Institute for Plant Breeding Research (MPIPZ) in Cologne, Germany invites applications for a postdoctoral position and a PhD position in the field of molecular plant-microbe interactions and computational biology. The postdoctoral position is available in the Max Planck Research Group on Fungal Biodiversity headed by Dr Eric Kemen. The PhD position is a shared project between the Max Planck Research Group on Resistance Pathway Dynamics in Plant Immunity headed by Dr Jane Parker and the group of Dr Eric Kemen. Background / Objectives Our focus is to unravel mechanisms in plant-microbe and microbe-microbe interactions that shape microbial community networks. For this, we work on the model plant Arabidopsis thaliana and have collected samples over several years from field plantings and wild populations. We have accessed a significant number of microbial isolates covering bacteria, fungi and protists. Using various high throughput sequencing techniques, we are characterizing microbial diversity and microbial functions and using statistical approaches to infer community structures. Models built from these data are used to generate hypothesis which are tested using reconstitution biology in gnotobiotic systems to reconstruct microbial networks in the laboratory. These approaches are combined with plant genetics to identify molecular mechanisms relevant for evolving and structuring microbial communities on plants. The selected candidates will use a combination of molecular biology, microbiology, genetics and computational biology. The candidates will be involved in sampling trips in the field, processing of samples for sequencing and computational data analyses, as well as microbial reconstitution assays. Methods will be adapted and developed according to needs for rigorously testing inferred hypothesis. Payment / Position The post-doctoral position for this project is available from October 01, 2016 for an initial period of one year and renewable depending on performance. The PhD position is available immediately. Salary and benefits are commensurate with public service organization rules (TVöD). The Max Planck Society is an equal opportunity employer. Their goal is to enhance the percentage of women where they are underrepresented. Women, therefore, are especially encouraged to apply. The Society is committed to employing more handicapped people. Applications of handicapped people are particularly welcome.
Up to EG 14 TVöD: Max Planck Institute for Infection Biology: The Department „Regulation in Infection Biology“ headed by Max Planck Director Prof. Emmanuelle Charpentier is seeking a Post-doc (Bioinformatics) ... Berlin (DE)
The Archaeogenetics department at the Max Planck Institute for the Science of Human History in Jena, Germany, is offering multiple PhD positions beginning October 2015. The overarching research topic at the institute is the use of novel scientific approaches from high throughput sequencing of ancient DNA from human populations and...more...